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Merck: EU approves Keytruda in new indications

( - Merck today announced that the European Commission has approved Keytruda as a treatment for five new indications, including certain colorectal cancers, advanced or recurrent endometrial carcinoma, and unresectable or metastatic stomach, small bowel or biliary tract cancers.

As a single agent, Keytruda acts on mismatches (dMMR) or high microsatellite instability (MSI-H).

Keytruda monotherapy has shown high objective response rates and durability of response in patients with five different types of MSI-H/dMMR cancers, an immuno-oncologist in Paris said.

This approval enables Keytruda monotherapy to be marketed in the 27 European Union (EU) Member States plus Iceland, Liechtenstein, Norway and Northern Ireland.

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