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GSK: encouraging results in multiple myeloma

( - GSK today announced positive results from an interim efficacy analysis of a phase III trial evaluating belantamab mafodotine as a second-line treatment for relapsed or refractory multiple myeloma.

The trial met its primary endpoint of progression-free survival (PFS) and showed that belantamab mafodotine, when combined with bortezomib plus dexamethasone (BorDex), significantly prolonged time to disease progression or death compared to daratumumab plus BorDex, an existing standard of care for relapsed/refractory multiple myeloma.

"We are particularly encouraged by the potential of belantamab mafodotin, when combined with BorDex, to address the high unmet need in relapsed/refractory multiple myeloma, given the direct comparison with the standard daratumumab-based regimen," commented Hesham Abdullah, Senior Vice President, Global Head of Oncology, R&D at GSK.

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