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Novartis: signs deal to develop Covid cell therapy

(CercleFinance.com) - Novartis said on Friday that it has signed an exclusive agreement with Mesoblast to further develop a cell therapy for acute respiratory distress syndrome, including that associated with Covid-19.


Under the license deal, Novartis will acquire the exclusive global rights to commercialise and manufacture Mesoblast's remestemcel-L for acute respiratory distress syndrome, an area which is currently largely unmet, with a mortality rate of approximately 40%.

As of now, the current standard of care includes prolonged intensive care treatment and mechanical ventilation.

In March, a trial including 12 patients with Covid-19 who were using mechanical ventilation was associated with an 83% survival rate.

The Swiss drugmaker said it will also obtain access to an Mesoblast's cell-therapy platform with a range of potential applications in severe respiratory conditions and beyond.

Novartis will make a 25 million dollar upfront payment and invest 25 million dollars in Mesoblast's capital, with additional payments and royalties depending on regulatory and commercial milestones.

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