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Novartis: continued efficacy demonstrated in breast cancer.

(CercleFinance.com) - Novartis today unveiled updated findings from a phase III study that reinforce the efficacy and safety of Kisqali plus letrozole in advanced or metastatic breast cancer.


After an additional 11 months of follow-up, a median progression-free survival (PFS) of 25.3 months for Kisqali plus letrozole was observed, and 16 months for letrozole alone.

After two years of treatment, the progression-free survival rate was 54.7% in the Kisqali plus letrozole arm compared to 35.9% in patients treated with letrozole alone.

The study comprised postmenopausal women with hormone receptor positive, human epidermal growth factor receptor-2 negative (HR+/HER2-) advanced or metastatic breast cancer.

This data will be presented to the Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago on Sunday 4 June.

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