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GlaxoSmithKline: tuberculosis vaccine shows promise in trial

(CercleFinance.com) - A GlaxoSmithKline candidate vaccine has produced a sustained level of protection against active pulmonary tuberculosis, the British drugmaker said on Tuesday.


GSK's M72/AS01E has significantly reduced the incidence of pulmonary tuberculosis disease in HIV-negative adults with latent tuberculosis infection, the company said.

These results demonstrate an overall vaccine efficacy of 50% for a period of three years after vaccination, it added.

The trial was conducted in Kenya, South Africa and Zambia and involved 3,573 HIV-negative adults aged from 18 to 50.

Tuberculosis is the leading cause of death through infectious disease worldwide, killing 1.5 million people in 2018.

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