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Roche: leukaemia drug benefits patients in phase III study

(CercleFinance.com) - Patients with chronic lymphocytic leukaemia who received Venclexta/Venclyxto plus MabThera/Rituxan lived significantly longer without their disease worsening, Roche said on Tuesday.

The Swiss drugmaker said phase III data showed that the chemotherapy-free combination reduced the risk of disease progression or death by 83% compared to a standard of care regimen in previously treated chronic lymphocytic leukaemia.

At two years, 84.9% of patients in the Venclexta/Venclyxto plus MabThera/Rituxan arm had not experienced disease progression, compared to 36.3% of patients in the control arm receiving bendamustine.

The study included 389 patients who had previously been treated with at least one, but not more than three lines of therapy.

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